Description

2,3-Piperazinedione, 1-(Chloroacetyl)-4-Ethyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize complex target structures for drug discovery programs and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry to explore new chemical entities with potential biological activity.
• Peptidomimetic Synthesis: Acts as a constrained scaffold or a diketopiperazine (DKP) analog in the design of peptide mimics to enhance metabolic stability and bioavailability.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental research in organic chemistry and heterocyclic compound development.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-value fine chemicals and advanced intermediates for specific client projects.

Basic Information

Product Name	2,3-Piperazinedione, 1-(Chloroacetyl)-4-Ethyl- (9Ci)
CAS No.	199387-10-5
Molecular Formula	C8H11ClN2O3
Molecular Weight	218.64 g/mol
Synonyms	1-(Chloroacetyl)-4-ethylpiperazine-2,3-dione; 4-Ethyl-1-(chloroacetyl)piperazine-2,3-dione; 1-Chloroacetyl-4-ethyl-2,3-piperazinedione; N-(Chloroacetyl)-4-ethyl-2,3-diketopiperazine; 4-Ethyl-1-(2-chloro-2-oxoethyl)piperazine-2,3-dione; Ethyl-chloroacetyl diketopiperazine; DKP derivative 199387-10-5
EINECS	Contact for details

Quality Control

Our 2,3-Piperazinedione, 1-(Chloroacetyl)-4-Ethyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.