Description

2-Piperazinecarboxylicacid,1,1-Dimethylethylester,(S)-(9Ci) is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for constructing complex molecules with high biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent drug candidates, especially protease inhibitors and receptor modulators.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Peptidomimetic Development: Integral for creating peptide analogs and mimetics with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-Piperazinecarboxylicacid,1,1-Dimethylethylester,(S)-(9Ci)
CAS No.	198992-48-2
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	(S)-1-Boc-2-piperazinecarboxylic acid; (S)-1-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid; (S)-N-Boc-piperazine-2-carboxylic acid; tert-Butyl (S)-piperazine-2-carboxylate; 1-Boc-(S)-piperazine-2-carboxylic acid; (S)-2-Piperazinecarboxylic acid 1-(1,1-dimethylethyl) ester; (S)-1-N-Boc-piperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylicacid,1,1-Dimethylethylester,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.