Description

Piperazinone, 3-(Phenylmethyl)-, (3R)- (9Ci) is a chiral piperazinone derivative, a high-value synthetic intermediate of significant interest in advanced organic synthesis. Its defined stereochemistry at the 3-position makes it a crucial building block for constructing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of potential therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Synthesis: Employed as a building block in stereoselective synthesis to introduce the (R)-configured piperazinone moiety into target molecules.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis or as a precursor for metal-organic frameworks (MOFs).
• Agrochemical Research: Investigated as an intermediate in the synthesis of novel crop protection agents with specific biological activity.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Fine Chemical Production: Incorporated into the multi-step synthesis of specialty chemicals requiring high purity and defined stereochemistry.

Basic Information

Product Name	Piperazinone, 3-(Phenylmethyl)-, (3R)- (9Ci)
CAS No.	198973-87-4
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	(3R)-3-Benzylpiperazin-2-one; (R)-3-Benzylpiperazin-2-one; 3-Benzyl-2-piperazinone, (R)-; 2-Piperazinone, 3-(phenylmethyl)-, (3R)-; (R)-3-Benzyl-2-oxopiperazine; (R)-3-Benzylpiperazine-2-one; (3R)-3-Benzyl-3,4-dihydro-2(1H)-pyrazinone
EINECS	Contact for details

Quality Control

Our Piperazinone, 3-(Phenylmethyl)-, (3R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.