Description

(2R,5S)-1-Benzyl-2,5-Dimethylpiperazine 2Hcl is a high-purity, stereochemically defined chiral piperazine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and chiral building block for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is paramount for biological activity and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Ligand and Catalyst Precursor: Used in the preparation of chiral ligands for asymmetric synthesis and catalysis.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereoselective pesticides and herbicides.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereocenters.

Basic Information

Product Name	(2R,5S)-1-Benzyl-2,5-Dimethylpiperazine 2Hcl
CAS No.	198896-00-3
Molecular Formula	C13H22Cl2N2
Molecular Weight	277.23 g/mol
Synonyms	(2R,5S)-1-Benzyl-2,5-dimethylpiperazine dihydrochloride; 1-Benzyl-2,5-dimethyl-(2R,5S)-piperazine dihydrochloride; (2R,5S)-1-Benzyl-2,5-dimethylpiperazine hydrochloride (1:2); (2R,5S)-1-Benzyl-2,5-dimethylpiperazine 2HCl; 1-Benzyl-2,5-dimethyl-(2R,5S)-piperazine 2HCl; (2R,5S)-1-Benzyl-2,5-dimethylpiperazine dihydrochloride salt; (2R,5S)-1-Bn-2,5-Dimethylpiperazine 2HCl
EINECS	Contact for details

Quality Control

Our (2R,5S)-1-Benzyl-2,5-Dimethylpiperazine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.