Description

1-Piperazineethanol, 4-Phenyl-α-(1-Pyrrolidinyl)Methyl)-, Dihydrochloride is a high-purity, fine chemical intermediate with a complex molecular structure. This compound matters for its role as a critical building block in advanced pharmaceutical synthesis, particularly for active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and life sciences industries for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those with neurological activity.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Serves as a building block in the multi-step production of Active Pharmaceutical Ingredients (APIs).
• Chemical Biology: Potential use in the development of biochemical probes and tool compounds for target validation.
• Custom Synthesis: Starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds.

Basic Information

Product Name	1-Piperazineethanol, 4-Phenyl-α-(1-Pyrrolidinyl)Methyl)-, Dihydrochloride
CAS No.	198767-56-5
Molecular Formula	C17H27N3O • 2HCl
Molecular Weight	362.34 g/mol (as free base: 289.42 g/mol)
Synonyms	4-Phenyl-α-(1-pyrrolidinyl)methyl-1-piperazineethanol dihydrochloride; 1-Piperazineethanol, 4-phenyl-α-(1-pyrrolidinyl)methyl-, dihydrochloride; 4-Phenyl-α-(pyrrolidin-1-ylmethyl)piperazin-1-ylethanol dihydrochloride; (4-Phenyl-α-(pyrrolidin-1-ylmethyl)-1-piperazinyl)ethanol dihydrochloride; 1-(2-Hydroxyethyl)-4-[(phenyl)(1-pyrrolidinyl)methyl]piperazine dihydrochloride; 198767-56-5; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1-Piperazineethanol, 4-Phenyl-α-(1-Pyrrolidinyl)Methyl)-, Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.