Description

Parecoxib Sodium CAS NO 198470-85-8 is a highly selective cyclooxygenase-2 (COX-2) inhibitor prodrug, designed for rapid conversion to its active metabolite, valdecoxib. This compound is of significant commercial interest for its targeted mechanism of action, offering potent analgesic and anti-inflammatory effects with a potentially improved safety profile. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of injectable post-operative pain management medications.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of injectable analgesics for the management of acute post-operative pain.
• Research & Development: Critical reference standard and intermediate in pharmacological studies exploring COX-2 inhibition and novel pain therapeutics.
• Analytical Standard: Used as a high-purity standard in quality control laboratories for HPLC, LC-MS, and other analytical method development and validation.
• Formulation Development: Serves as a key material for pre-formulation studies, stability testing, and the development of parenteral dosage forms.

Basic Information

Product Name	Parecoxib Sodium
CAS No.	198470-85-8
Molecular Formula	C19H17N2O4SNa
Molecular Weight	392.40 g/mol
Synonyms	Parecoxib Sodium Salt; SC 69124A; Dynastat (Brand Name); 4-[5-Methyl-3-phenyl-4-isoxazolyl]benzenesulfonamide, N-[[(4-morpholinyl)carbonyl]oxy]-, sodium salt; Valdecoxib Prodrug; COX-2 Inhibitor Prodrug; Parecoxibum Natricum
EINECS	Contact for details

Quality Control

Our Parecoxib Sodium is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity (by HPLC), and related substances. We adhere to cGMP principles to ensure supply reliability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.