Description

Parecoxib CAS NO 198470-84-7 is a selective cyclooxygenase-2 (COX-2) inhibitor prodrug, valued for its targeted anti-inflammatory and analgesic properties. It is a critical pharmaceutical intermediate used in the synthesis of active pharmaceutical ingredients (APIs) for post-operative pain management. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries requiring high-purity building blocks for injectable formulations.

Application

• Pharmaceutical API Synthesis: Primary use as a key intermediate in the manufacture of the active metabolite, valdecoxib.
• Analgesic Drug Development: Serves as a core component in research and production of short-term, post-surgical pain management medications.
• Anti-inflammatory Formulations: Used in the development of injectable drugs designed to reduce inflammation with a targeted COX-2 mechanism.
• Clinical Research Materials: Supplied as a high-purity reference standard for pharmacokinetic and pharmacodynamic studies.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized pharmaceutical clients.

Basic Information

Product Name	Parecoxib
CAS No.	198470-84-7
Molecular Formula	C19H18N2O4S
Molecular Weight	370.42 g/mol
Synonyms	Parecoxib Sodium; SC 69124; Valdecoxib Prodrug; 3-(4-Methylphenyl)-4-(4-sulfamoylphenyl)-2(5H)-furanone, 5-(N,N-Dimethylcarbamoyl) Derivative; Dynastat (Brand Name); Parecoxibum; Parecoxibum [Latin]; APO-Parecoxib
EINECS	Contact for details

Quality Control

Our Parecoxib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.