Description

1-Boc-4-(4-Formylphenyl)Piperazine is a high-purity, protected piperazine derivative featuring a formylphenyl group, serving as a critical building block in modern organic synthesis. This compound is essential for the efficient construction of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly those targeting CNS disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its versatile reactive sites (Boc-protected amine and aldehyde).
• Peptidomimetic Synthesis: Employed in the design and synthesis of peptidomimetics and constrained peptides to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Agrochemical Active Ingredient Synthesis: Utilized in the development of new herbicides, fungicides, and insecticides.
• Polymer and Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored properties.

Basic Information

Product Name	1-Boc-4-(4-Formylphenyl)Piperazine
CAS No.	197638-83-8
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	1-Boc-4-(4-Formylphenyl)piperazine; tert-Butyl 4-(4-formylphenyl)piperazine-1-carboxylate; 4-(4-Formylphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(4-formylphenyl)piperazine; N-Boc-4-(4-formylphenyl)piperazine; 4-Formylphenylpiperazine-1-carboxylic acid tert-butyl ester; Piperazine, 1-[(1,1-dimethylethoxy)carbonyl]-4-(4-formylphenyl)-
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(4-Formylphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.