Description

tert-Butyl 4-(4-Ethoxy-4-Oxobutyl)Piperazine-1-Carboxylate CAS NO 197585-40-3 is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the pharmaceutical sector where precise molecular architecture is paramount. This intermediate is essential for research chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require complex amine functionalities.
• Peptidomimetics & Bioactive Molecule Development: The piperazine core and protected functional groups make it ideal for constructing peptide mimics and other biologically active compounds.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring high-fidelity building blocks.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry laboratories.

Basic Information

Product Name	tert-Butyl 4-(4-Ethoxy-4-Oxobutyl)Piperazine-1-Carboxylate
CAS No.	197585-40-3
Molecular Formula	C15H28N2O4
Molecular Weight	300.40 g/mol
Synonyms	1-Boc-4-(4-Ethoxy-4-oxobutyl)piperazine; tert-Butyl 4-(4-ethoxy-4-oxobutyl)piperazine-1-carboxylate; 4-(1-Boc-piperazin-4-yl)butyric acid ethyl ester; 1-(tert-Butoxycarbonyl)-4-(4-ethoxy-4-oxobutyl)piperazine; Ethyl 4-(4-((tert-butoxycarbonyl)amino)butyl)piperazine-1-carboxylate (alternative); BOC-Piperazine butyric acid ethyl ester; 197585-40-3; Piperazine, 1-(1,1-dimethylethyl) 4-(4-ethoxy-1,4-dioxobutyl)-, 1,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(4-Ethoxy-4-Oxobutyl)Piperazine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We maintain compliance with relevant standards for fine chemical intermediates, and custom synthesis to specific purity grades (e.g., >97%, >98%, >99%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.