Description

1,3-Didocosahexaenoyl-2-Palmitoyl Glycerol is a structured triglyceride (TAG) of significant scientific and commercial interest, featuring two docosahexaenoic acid (DHA) residues and one palmitic acid residue in a specific positional arrangement. This molecular architecture is engineered to mimic the lipid profile of human breast milk and is critical for enhancing the bioavailability and functional delivery of ω-3 fatty acids. It is primarily sought by manufacturers in the nutraceutical, infant formula, and pharmaceutical industries for advanced lipid-based formulations.

Application

• Infant Formula & Nutritional Supplements: As a key structural lipid to closely replicate the fat composition and digestibility of human milk fat.
• Pharmaceutical Excipients: Used in lipid-based drug delivery systems (e.g., self-emulsifying drug delivery systems - SEDDS) to improve the solubility and absorption of poorly water-soluble active pharmaceutical ingredients (APIs).
• Clinical Nutrition: A vital component in medical nutrition products and parenteral emulsions designed for patients with specific metabolic needs or malabsorption issues.
• Cognitive Health Supplements: Targeted delivery vehicle for DHA to support brain and neurological development and function.
• Cosmetic & Dermal Applications: Employed in high-end skincare formulations for its emollient properties and potential skin barrier repair benefits.
• Biochemical Research: Serves as a standard or substrate in lipidomics research, metabolic studies, and enzymatic assays.

Basic Information

Product Name	1,3-Didocosahexaenoyl-2-Palmitoyl Glycerol
CAS No.	197016-86-7
Molecular Formula	C71H114O6
Molecular Weight	1063.7 g/mol
Synonyms	1,3-Di-DHA-2-Palmitin; DHA-DHA-Palmitin; TAG (DHA, DHA, PA); 1,3-Bis(docosahexaenoyl)-2-palmitoyl-glycerol; sn-1,3-Didocosahexaenoyl-2-palmitoyl-rac-glycerol; Structured Triglyceride OPO (DHA variant); Betapol®-type DHA analog; Glycerol triester (DHA, DHA, C16:0)
EINECS	Contact for details

Quality Control

Our 1,3-Didocosahexaenoyl-2-Palmitoyl Glycerol is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including advanced chromatographic methods, to ensure high positional purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) detailing purity, fatty acid profile, and critical impurities. Production can adhere to cGMP guidelines for pharmaceutical and nutraceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the product to reach room temperature in a desiccator before opening to minimize moisture condensation. Keep away from heat and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oily liquid
Identification (HPLC/GC)	Complies
Assay (HPLC)	≥ 95.0% (Total structured TAG)
Positional Purity (sn-2 Palmitate)	≥ 50.0%
Docosahexaenoic Acid (DHA) Content	≥ 45.0% (of total fatty acids)
Peroxide Value (PV)	≤ 5.0 meq/kg
Anisidine Value (p-AV)	≤ 20.0
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Microbiological Count	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.