Description

Farglitazar is a potent and selective peroxisome proliferator-activated receptor (PPAR) agonist, specifically targeting the PPARγ subtype. This compound is of significant interest in pharmaceutical research for its potential role in modulating metabolic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for metabolic disorders. The material is supplied as a high-purity reference standard and active pharmaceutical ingredient (API) intermediate.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block in the discovery and development of new drugs targeting PPAR receptors.
• Metabolic Disorder Studies: Used as a pharmacological tool in preclinical research to investigate pathways related to diabetes, dyslipidemia, and insulin resistance.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and in vitro assays to evaluate PPARγ agonist activity and selectivity.
• API Synthesis: Functions as a key synthetic intermediate in the production of active pharmaceutical ingredients for metabolic disease therapeutics.
• Academic Research: Utilized in university and institutional labs for fundamental studies on nuclear receptor biology and signal transduction.

Basic Information

Product Name	Farglitazar
CAS No.	196808-45-4
Molecular Formula	C24H21F3N2O4S
Molecular Weight	490.50 g/mol
Synonyms	Farglitazar; GW-409544; GW409544; 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; (R)-5-(4-(2-(5-Ethyl-2-pyridyl)ethoxy)benzyl)thiazolidine-2,4-dione; PPARγ agonist GW-409544; PPAR gamma agonist
EINECS	Contact for details

Quality Control

Our Farglitazar is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.