Description

(S)-n-[2-[2,3-Dihydro-6-Hydroxy-7-(2-Hydroxyethyl)-1H-Inden-1-Yl]Ethyl]Propanamide is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its defined stereochemistry and functional groups make it a critical building block for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of complex, stereospecific drug molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of proprietary APIs, particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Employed as a precursor in catalytic asymmetric reactions to construct complex molecular architectures with defined three-dimensional structures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Prodrug Development: Its functional groups allow for its use in designing targeted drug delivery systems and prodrug formulations.

Basic Information

Item	Detail
Product Name	(S)-n-[2-[2,3-Dihydro-6-Hydroxy-7-(2-Hydroxyethyl)-1H-Inden-1-Yl]Ethyl]Propanamide
CAS No.	196597-88-3
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	(S)-N-[2-(6-Hydroxy-7-(2-hydroxyethyl)-2,3-dihydro-1H-inden-1-yl)ethyl]propanamide; (S)-N-[2-[6-Hydroxy-7-(2-hydroxyethyl)-2,3-dihydro-1H-inden-1-yl]ethyl]propionamide; (S)-N-[2-(6-Hydroxy-7-(2-hydroxyethyl)-2,3-dihydroinden-1-yl)ethyl]propanamide; (S)-1-[2-(Propionylamino)ethyl]-6-hydroxy-7-(2-hydroxyethyl)-2,3-dihydro-1H-indene; 196597-88-3; (S)-enantiomer of the indene propanamide derivative.
EINECS	Contact for details

Quality Control

Our production of (S)-n-[2-[2,3-Dihydro-6-Hydroxy-7-(2-Hydroxyethyl)-1H-Inden-1-Yl]Ethyl]Propanamide adheres to stringent quality protocols suitable for pharmaceutical R&D and cGMP applications. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure high stereochemical and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.