Description

Hexadecanoic Acid, (1S)-1-Bis(1-Methylethyl)Amino(Phenylmethoxy)Phosphinooxymethyl-1,2-Ethanediyl Ester is a specialized organophosphorus derivative of palmitic acid, designed for advanced synthetic applications. This high-purity intermediate is critical for researchers and manufacturers requiring precise molecular architecture in complex chemical syntheses. It is primarily utilized in the development of novel pharmaceuticals, agrochemicals, and sophisticated materials where its unique phosphonate ester functionality enables targeted reactivity and serves as a key building block.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and neurological pathways.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its lipid-like properties for enhanced bioavailability.
• Chemical Biology & Proteomics: Serves as a precursor for synthesizing activity-based probes (ABPs) and affinity labels to study enzyme mechanisms, especially phosphatases and esterases.
• Material Science: Employed in the creation of specialized surfactants, lubricant additives, and polymer modifiers where the phosphonate group imparts specific surface activity or stability.
• Process Chemistry & Catalysis: Acts as a ligand precursor or a substrate in catalytic reactions, including asymmetric synthesis and cross-coupling methodologies.

Basic Information

Item	Details
Product Name	Hexadecanoic Acid, (1S)-1-Bis(1-Methylethyl)Amino(Phenylmethoxy)Phosphinooxymethyl-1,2-Ethanediyl Ester
CAS No.	196304-47-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S)-1-[(Diisopropylamino)(benzyloxy)phosphinyl]oxy-2-[(1-oxohexadecyl)oxy]ethane; Palmitic Acid (1S)-1-[(Benzyloxy)diisopropylphosphoramidoyl]oxymethyl-2-hydroxyethyl Ester; Phosphoramidate Ester of Palmitic Acid; CAS 196304-47-9; (S)-Isomer of Hexadecanoic Acid Phosphoramidate Ester; Diisopropyl (Benzyl) Phosphoramidate Derivative of Palmitic Acid Glycol Ester
EINECS	Contact for details

Quality Control

Every batch of Hexadecanoic Acid, (1S)-1-Bis(1-Methylethyl)Amino(Phenylmethoxy)Phosphinooxymethyl-1,2-Ethanediyl Ester is produced and tested under a strict quality management system. We guarantee high chemical and chiral purity, verified by advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.