Description

Omtriptolide is a bioactive diterpenoid compound with significant research and development interest. Its unique molecular structure makes it a valuable reference standard and a key intermediate for advanced pharmaceutical synthesis. This high-purity compound is essential for researchers and manufacturers in the life sciences sector, particularly those focused on oncology and anti-inflammatory drug discovery. Global B2B clients rely on our supply for its consistent quality and reliable documentation.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical method development and quality control for drug substance analysis.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the multi-step synthesis of novel therapeutic agents.
• Biochemical Research: Employed in in vitro and cellular assays to study biological pathways, mechanism of action, and structure-activity relationships (SAR).
• Preclinical Development: Utilized in formulation studies and pharmacokinetic/pharmacodynamic (PK/PD) modeling during early-stage drug candidate evaluation.
• Academic Research: Supports chemical biology and medicinal chemistry programs in universities and research institutes worldwide.

Basic Information

Product Name	Omtriptolide
CAS No.	195883-06-8
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	(5R,5aR,8aS,9R)-9-Hydroxy-5,8a-dimethyl-3-methylene-5,5a,6,7,8,8a,9,10-octahydro-11H-5,9-epoxynaphtho[2,3-b]oxepin-11-one; OMT; Tripdiolide analog; 14-Deoxy-14,15-dehydrotriptolide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Omtriptolide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and strength, meeting the exacting standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting results from tests including HPLC purity, related substances, residual solvents, and identity confirmation (IR, MS). Our quality commitment supports your regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation risk. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.