Description

(S)-1-Boc-4-(2-Cbz-Amino-2-Methoxycarbonyl-Ethyl)Piperidine is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is critically important for the development of novel pharmaceuticals, particularly in the construction of complex peptide-based drug candidates and enzyme inhibitors. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of peptidomimetics and protease inhibitors.
• Medicinal Chemistry Research: Used in the design and construction of novel drug candidates targeting neurological and metabolic diseases.
• Peptide Synthesis: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block to introduce stereocenters in complex molecular architectures.
• Chemical Biology: Used in the development of activity-based probes and molecular tools for studying biological pathways.
• Process Development: Serves as a reference standard and starting material for scaling up API manufacturing processes.

Basic Information

Product Name	(S)-1-Boc-4-(2-Cbz-Amino-2-Methoxycarbonyl-Ethyl)Piperidine
CAS No.	195877-54-4
Molecular Formula	C22H32N2O6
Molecular Weight	420.50 g/mol
Synonyms	1-Boc-4-[(2S)-2-[[(Benzyloxy)carbonyl]amino]-2-methoxy-2-oxoethyl]piperidine; (S)-1-(tert-Butoxycarbonyl)-4-[2-[(benzyloxycarbonyl)amino]-2-methoxy-2-oxoethyl]piperidine; (S)-1-Boc-4-(2-Cbz-amino-2-methoxycarbonyl-ethyl)piperidine; tert-Butyl (S)-4-(2-((benzyloxycarbonyl)amino)-2-methoxy-2-oxoethyl)piperidine-1-carboxylate; (S)-Boc-4-(Cbz-Asp(OMe)-Piperidine; (S)-N-Boc-4-(N-Cbz-2-amino-2-methoxycarbonylethyl)piperidine; (S)-1-Boc-4-(2-Cbz-Amino-2-Methoxycarbonyl-Ethyl)Piperidine; 195877-54-4
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-4-(2-Cbz-Amino-2-Methoxycarbonyl-Ethyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.