Description

4-Piperidinemethanol,3-Hydroxy-,(3R,4R)-Rel- is a high-purity, stereochemically defined chiral piperidine derivative. This compound serves as a critical chiral building block and synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities, especially for neurological and psychiatric targets.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical transformations.
• Process Chemistry Development: Serves as a starting material for scaling up the production of candidate drugs.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and protein function.
• Fine Chemical Synthesis: A building block for creating other specialized, high-value fine chemicals and catalysts.

Basic Information

Product Name	4-Piperidinemethanol,3-Hydroxy-,(3R,4R)-Rel-
CAS No.	195628-18-3
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(3R,4R)-3-Hydroxypiperidin-4-ylmethanol; rel-(3R,4R)-3-Hydroxy-4-piperidinemethanol; (3R,4R)-3-Hydroxy-4-(hydroxymethyl)piperidine; 4-Piperidinemethanol, 3-hydroxy-, (3R,4R)-rel-; 3-Hydroxy-4-piperidinemethanol (rel-(3R,4R)-isomer); Chiral 3-Hydroxy-4-piperidinemethanol; (R,R)-3-Hydroxy-4-piperidinemethanol (relative configuration)
EINECS	Contact for details

Quality Control

Our 4-Piperidinemethanol,3-Hydroxy-,(3R,4R)-Rel- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including chiral purity and chemical identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.