Description

n-Acetoyl-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, a key intermediate in the biosynthesis of complex glycosphingolipids and ceramides. This compound is critical for biochemical research focused on understanding cell signaling, apoptosis, and membrane structure. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutics and diagnostic tools.

Application

• Biochemical Research: A fundamental building block for studying sphingolipid metabolism, cell proliferation, and programmed cell death (apoptosis) pathways.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of more complex sphingolipid-based drug candidates targeting cancer, inflammation, and neurological disorders.
• Lipidomics Standards: Used as a certified reference standard in mass spectrometry for the accurate identification and quantification of sphingolipids in biological samples.
• Cell Culture & Signaling Studies: Employed to modulate ceramide levels in vitro to investigate their role in cellular stress responses and signal transduction.
• Cosmeceutical R&D: Investigated for its potential application in advanced skincare formulations aimed at improving skin barrier function and cellular repair.

Basic Information

Product Name	n-Acetoyl-D-Erythro-Sphingosine
CAS No.	195194-58-2
Molecular Formula	C20H39NO4
Molecular Weight	357.54 g/mol
Synonyms	N-Acetyl-D-erythro-sphingosine; C2-Ceramide; D-erythro-C2-Ceramide; N-Acetylsphingosine; N-Acetyl-D-sphingosine; N-Acetylceramide; Ceramide C2; (2S,3R,4E)-2-Acetamido-4-octadecene-1,3-diol
EINECS	Contact for details

Quality Control

Our n-Acetoyl-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.