Description

tert-Butyl 4-((4-Fluorophenyl)Sulfonyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound serves as a critical building block for the synthesis of complex molecules, particularly in the creation of kinase inhibitors and other targeted therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially kinase inhibitors.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Essential for academic and industrial research focused on oncology, neurology, and inflammatory disease pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Process Chemistry: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	tert-Butyl 4-((4-Fluorophenyl)Sulfonyl)Piperazine-1-Carboxylate
CAS No.	194853-66-2
Molecular Formula	C15H21FN2O4S
Molecular Weight	344.40 g/mol
Synonyms	1-Boc-4-(4-Fluorobenzenesulfonyl)piperazine; tert-Butyl 4-(4-Fluorophenylsulfonyl)piperazine-1-carboxylate; 4-(4-Fluorobenzenesulfonyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(4-fluorophenyl)sulfonyl]piperazine; N-Boc-4-(4-fluorophenylsulfonyl)piperazine; 194853-66-2; BOC-4-(4-Fluorophenylsulfonyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((4-Fluorophenyl)Sulfonyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.