Description

5-Chloro-3-Cyanoindole is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique indole scaffold, functionalized with both chloro and cyano groups, provides versatile reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, leveraging its halogenated indole core.
• Material Science Precursor: Serves as a building block for organic electronic materials, dyes, and pigments due to its conjugated system.
• Academic & R&D: Employed in methodological studies and as a standard in heterocyclic chemistry research within university and corporate laboratories.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	5-Chloro-3-Cyanoindole
CAS No.	194490-14-7
Molecular Formula	C9H5ClN2
Molecular Weight	176.60 g/mol
Synonyms	5-Chloro-1H-indole-3-carbonitrile; 3-Cyano-5-chloroindole; 5-Chloroindole-3-carbonitrile; 1H-Indole-3-carbonitrile, 5-chloro-; 194490-14-7; 5-Chloro-3-cyano-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Cyanoindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.