Description

1-Ethyl-4-(tert-Butyloxycarbonyl)Piperazin-2-One is a high-purity, protected piperazinone derivative, a crucial building block in modern pharmaceutical synthesis. Its primary value lies in serving as a versatile and reactive intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a protected piperazinone moiety.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design and synthesis of peptidomimetics and protease inhibitors.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs).

Basic Information

Product Name	1-Ethyl-4-(tert-Butyloxycarbonyl)Piperazin-2-One
CAS No.	194350-95-3
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	1-Ethyl-4-(Boc)piperazin-2-one; 4-(tert-Butoxycarbonyl)-1-ethylpiperazin-2-one; 1-Ethyl-4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-2-one; 1-Ethyl-4-(BOC)piperazin-2-one; 2-Piperazinone, 1-ethyl-4-[(1,1-dimethylethoxy)carbonyl]-; N-Ethyl-4-(tert-butoxycarbonyl)-2-piperazinone; Boc-1-Ethyl-piperazin-2-one; 194350-95-3
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-(tert-Butyloxycarbonyl)Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We adhere to cGMP guidelines where applicable to support our customers' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.