Description

1-Methylpiperazin-2-One Trifluoroacetate is a high-purity organic salt, specifically the trifluoroacetate salt of 1-methyl-2-oxopiperazine, which serves as a critical synthetic intermediate and building block in advanced chemical synthesis. Its value lies in providing a protected, reactive, and isolable form of the 1-methyl-2-oxopiperazine moiety, facilitating precise and scalable manufacturing processes. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is utilized in the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those containing piperazine or piperidone pharmacophores.
• Agrochemical Research: Used in the development and scale-up of novel pesticides, herbicides, and fungicides.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and fine chemicals.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploratory chemistry.
• Peptidomimetics: Acts as a constrained scaffold or backbone component in the design of peptide mimics for therapeutic applications.
• Ligand Synthesis: Useful for creating specialized ligands for catalysis or metal coordination chemistry.

Basic Information

Product Name	1-Methylpiperazin-2-One Trifluoroacetate
CAS No.	194350-88-4
Molecular Formula	C7H11F3N2O3
Molecular Weight	228.17 g/mol
Synonyms	1-Methyl-2-oxopiperazine trifluoroacetate; 1-Methylpiperazin-2-one TFA salt; 1-Methyl-2-piperazinone trifluoroacetate; 1-Methyl-2-ketopiperazine trifluoroacetate; N-Methyl-2-oxopiperazine trifluoroacetate; 1-Methyl-2-oxohexahydropyrazine trifluoroacetate; 194350-88-4; TFA salt of 1-methyl-2-oxopiperazine
EINECS	Contact for details

Quality Control

Our 1-Methylpiperazin-2-One Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates, from research to commercial-scale GMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under dry conditions to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.