Description

(2S,5S)-2,5-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, chiral piperazine derivative that serves as a critical building block in modern organic synthesis. This compound matters because it provides a protected, stereochemically defined scaffold essential for constructing complex molecules with high enantiomeric purity. Pharmaceutical and agrochemical R&D teams need it for the development of new active ingredients, particularly in creating novel APIs and fine chemicals where precise stereochemistry is non-negotiable for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Integral for constructing constrained peptide analogs and macrocycles in medicinal chemistry.
• Custom Chemical Synthesis: Employed by CROs and CDMOs for client-specific projects requiring high chiral purity.
• Academic Research: A valuable reagent for methodological studies in organic chemistry and stereochemistry.

Basic Information

Product Name	(2S,5S)-2,5-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	194032-43-4
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	Boc-(2S,5S)-2,5-Dimethylpiperazine; (2S,5S)-1-Boc-2,5-Dimethylpiperazine; tert-Butyl (2S,5S)-2,5-dimethylpiperazine-1-carboxylate; 1-N-Boc-(2S,5S)-2,5-Dimethylpiperazine; (2S,5S)-2,5-Dimethyl-1-(tert-butoxycarbonyl)piperazine; (2S,5S)-1-(tert-Butoxycarbonyl)-2,5-dimethylpiperazine; (S,S)-1-Boc-2,5-Dimethylpiperazine; 194032-43-4
EINECS	Contact for details

Quality Control

Our (2S,5S)-2,5-Dimethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided to guarantee consistent quality and supply reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.