Description

1-Boc-4-(2-Chloro-4-Nitrophenyl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine ring system. This compound is critical for medicinal chemists as a versatile building block in the synthesis of complex molecules, particularly for drug discovery and development programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during early-stage drug discovery.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Chemical Library Development: Employed in combinatorial chemistry to create diverse compound libraries for high-throughput screening.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.
• Academic Research: Used in university and institutional labs for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	1-Boc-4-(2-Chloro-4-Nitrophenyl)Piperazine
CAS No.	193902-80-6
Molecular Formula	C15H20ClN3O4
Molecular Weight	341.79 g/mol
Synonyms	1-Boc-4-(2-Chloro-4-nitrophenyl)piperazine; tert-Butyl 4-(2-chloro-4-nitrophenyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-chloro-4-nitrophenyl)piperazine; 4-(2-Chloro-4-nitrophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Piperazine, 1-(2-chloro-4-nitrophenyl)-4-[(1,1-dimethylethoxy)carbonyl]-; 193902-80-6; N-Boc-4-(2-Chloro-4-nitrophenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2-Chloro-4-Nitrophenyl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.