Description

1-Boc-4-(5-Nitro-2-Pyridyl)Piperazine is a high-purity, advanced pharmaceutical intermediate and building block used in organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the construction of complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API development.
• Academic Research: Used in university and institutional laboratories for methodological development and exploratory synthetic chemistry.

Basic Information

Product Name	1-Boc-4-(5-Nitro-2-Pyridyl)Piperazine
CAS No.	193902-78-2
Molecular Formula	C14H20N4O4
Molecular Weight	308.34 g/mol
Synonyms	1-Boc-4-(5-nitropyridin-2-yl)piperazine; tert-Butyl 4-(5-nitro-2-pyridinyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(5-nitro-2-pyridyl)piperazine; 4-(5-Nitro-2-pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 2-(4-Boc-piperazin-1-yl)-5-nitropyridine; BOC-4-(5-Nitro-2-Pyridyl)Piperazine; 1-Boc-4-(5-Nitro-2-Pyridinyl)Piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(5-Nitro-2-Pyridyl)Piperazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.