Description

2,5-Piperazinedione,1-Acetyl-3,4-Dimethyl-,(S)-(9Ci) is a high-purity, chiral diketopiperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and synthetic intermediate for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key chiral scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a constrained dipeptide mimetic to explore structure-activity relationships (SAR) and improve peptide metabolic stability.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological studies.
• Academic & Industrial R&D: Fundamental building block for novel heterocyclic chemistry research in university and corporate laboratories.

Basic Information

Product Name	2,5-Piperazinedione,1-Acetyl-3,4-Dimethyl-,(S)-(9Ci)
CAS No.	193686-32-7
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	(S)-1-Acetyl-3,4-dimethylpiperazine-2,5-dione; (3S)-1-Acetyl-3,4-dimethyl-2,5-piperazinedione; 1-Acetyl-3,4-dimethyl-2,5-piperazinedione, (S)-; (S)-1-Acetyl-3,4-dimethyl-2,5-diketopiperazine; Acetylated (S)-3,4-dimethyl-2,5-diketopiperazine; Chiral acetyl-dimethyl-diketopiperazine; (S)-ADDP
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,1-Acetyl-3,4-Dimethyl-,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.