Description

3-Piperidinecarbonyl Chloride, 1-Methyl- (9Ci) is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a key building block for constructing complex nitrogen-containing heterocycles, which are fundamental scaffolds in modern pharmaceuticals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the piperidine moiety for enhanced biological activity.
• Chemical Research & Development: Serves as a versatile acyl chloride reagent for introducing the 1-methylpiperidine-3-carbonyl group into target molecules during structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other advanced catalytic processes.
• Material Science Applications: Potential building block for creating novel polymers or functionalized surfaces with specific chemical properties.

Basic Information

Item	Detail
Product Name	3-Piperidinecarbonyl Chloride, 1-Methyl- (9Ci)
CAS No.	193538-44-2
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	1-Methylpiperidine-3-carbonyl chloride; 1-Methyl-3-piperidinecarbonyl chloride; 1-Methyl-3-piperidyl carbonyl chloride; 3-(Chlorocarbonyl)-1-methylpiperidine; 1-Methyl-3-carbamoylpiperidine hydrochloride (precursor related); N-Methyl-3-piperidinecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Piperidinecarbonyl Chloride, 1-Methyl- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC or titration), identity (by IR/NMR), and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Due to its reactivity as an acid chloride and sensitivity to moisture, it is recommended to handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.