Description

Pyrrolo[1,2-A]Pyrazine-7-Methanol, Octahydro-, (7S,8As)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals, offering a rigid, fused bicyclic scaffold. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for new chemical entities (NCEs).
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to introduce complex stereochemistry.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialized agrochemicals or advanced material science components.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-7-Methanol, Octahydro-, (7S,8As)- (9Ci)
CAS No.	193067-63-9
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	(7S,8aS)-Octahydro-1H-pyrrolo[1,2-a]pyrazine-7-methanol; (7S,8aS)-Octahydropyrrolo[1,2-a]pyrazine-7-methanol; (7S,8aS)-Octahydro-1H-pyrrolo[1,2-a]pyrazin-7-ylmethanol; (7S,8aS)-1,2,3,4,6,7,8,8a-Octahydropyrrolo[1,2-a]pyrazine-7-methanol; (7S,8aR)-Octahydro-1H-pyrrolo[1,2-a]pyrazine-7-methanol (enantiomer); Pyrrolo[1,2-a]pyrazine-7-methanol, octahydro-, (7S,8aS)-; Chiral Pyrrolopyrazine Methanol Derivative
EINECS	Contact for details

Quality Control

Our Pyrrolo[1,2-A]Pyrazine-7-Methanol, Octahydro-, (7S,8As)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.