Description

(5Z,11Z,14Z)-8,9-Dihydroxyicosa-5,11,14-Trienoic Acid is a specialized dihydroxy fatty acid derivative, specifically an 8,9-diol of eicosatrienoic acid. This compound is a valuable biochemical intermediate and reference standard for research into lipid metabolism, eicosanoid signaling pathways, and inflammation. It is primarily utilized by pharmaceutical R&D departments, biochemical researchers, and manufacturers of high-purity analytical standards.

Application

• Biochemical Research Standard: Serves as a high-purity reference compound for analytical method development and validation in lipidomics studies.
• Pharmaceutical R&D: Used as a key intermediate or probe in the investigation of eicosanoid biosynthesis pathways and the development of related therapeutic agents.
• Cell Signaling Studies: Employed in vitro and in vivo research to study the biological roles of dihydroxy fatty acids in inflammation and cellular regulation.
• Enzymology Substrate: Acts as a substrate for enzymes like lipoxygenases and cytochrome P450s to study reaction mechanisms and kinetics.
• Metabolite Identification: Used as an authentic standard in mass spectrometry for the identification and quantification of endogenous metabolites.

Basic Information

Product Name	(5Z,11Z,14Z)-8,9-Dihydroxyicosa-5,11,14-Trienoic Acid
CAS No.	192461-96-4
Molecular Formula	C₂₀H₃₄O₄
Molecular Weight	338.48 g/mol
Synonyms	8,9-DiHETrE; 8,9-Dihydroxy-5Z,11Z,14Z-eicosatrienoic acid; 8,9-DHET; (5Z,11Z,14Z)-8,9-Dihydroxyeicosa-5,11,14-trienoic acid; 8,9-Dihydroxy-5,11,14-eicosatrienoic acid; Eicosa-5,11,14-trienoic acid, 8,9-dihydroxy-, (5Z,11Z,14Z)-
EINECS	Contact for details

Quality Control

Our (5Z,11Z,14Z)-8,9-Dihydroxyicosa-5,11,14-Trienoic Acid is produced under strict quality management protocols. Each batch is characterized and tested to ensure high chemical purity and structural identity, with comprehensive analysis via HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) providing purity, assay, and impurity profile is supplied with every order to guarantee reproducibility and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97% (by titration)
Water Content	≤ 0.5% (KF)
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.