Description

Methyl 3-Nitro-4-Piperazinobenzenecarboxylate CAS NO 192441-86-4 is a high-purity, advanced pharmaceutical intermediate characterized by its specific nitro and piperazine functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drug candidates and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Synthesis: Used in organic synthesis for constructing complex molecules containing nitro and piperazine moieties.
• Research & Development: Serves as a standard or reagent in medicinal chemistry for structure-activity relationship (SAR) studies.
• API Manufacturing: Employed in the scaled-up production of active pharmaceutical ingredients requiring this specific chemical framework.
• Fine Chemical Production: Utilized in the manufacture of specialized fine chemicals for advanced applications.

Basic Information

Product Name	Methyl 3-Nitro-4-Piperazinobenzenecarboxylate
CAS No.	192441-86-4
Molecular Formula	C12H15N3O4
Molecular Weight	265.27 g/mol
Synonyms	Methyl 3-nitro-4-(piperazin-1-yl)benzoate; 4-(Piperazin-1-yl)-3-nitrobenzoic acid methyl ester; Benzoic acid, 3-nitro-4-(1-piperazinyl)-, methyl ester; Methyl 4-(piperazin-1-yl)-3-nitrobenzoate; 1-Piperazinecarboxylic acid, 4-(3-nitro-4-(methoxycarbonyl)phenyl)-; Methyl 3-nitro-4-piperazin-1-ylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Nitro-4-Piperazinobenzenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.