Description

4-(2-Amino-Ethyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a primary amine and a tert-butyloxycarbonyl (Boc)-protected secondary amine, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Ligand Synthesis: Used to create sophisticated chelating agents and ligands for catalysis and metal complexation in industrial processes.
• Peptidomimetics & Scaffold Development: Employed in medicinal chemistry for constructing peptide analogs and privileged heterocyclic scaffolds to explore structure-activity relationships (SAR).
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Can be incorporated as a functional monomer or cross-linker to produce specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-(2-Amino-Ethyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	192130-34-0
Molecular Formula	C11H23N3O2
Molecular Weight	229.32 g/mol
Synonyms	1-Boc-4-(2-aminoethyl)piperazine; tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate; 4-(2-Aminoethyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-1-(2-aminoethyl)piperazine; 1-(2-Aminoethyl)piperazine-1-carboxylic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-4-(2-aminoethyl)piperazine; 2-(1-Boc-piperazin-4-yl)ethylamine
EINECS	Contact for details

Quality Control

Our 4-(2-Amino-Ethyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.