Description

(-)-n-[4-[4-[n-Ethyl-n-(6-Fluoro-6-Methylheptyl)Amino]-1(S)-Hydroxybutyl]Phenyl]Methanesulfonamide Fumarate (2:1) is a high-purity, non-racemic chiral compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its specific stereochemistry and functional groups, which are essential for synthesizing advanced active pharmaceutical ingredients (APIs) with targeted biological activity. This product is vital for research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents, particularly in areas requiring precise molecular configuration.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, especially those targeting neurological or cardiovascular pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and scale-up production of new chemical entities (NCEs).
• Chiral Synthesis: Used in asymmetric synthesis to introduce specific stereocenters into complex molecular architectures.
• Biochemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and receptor binding.
• Process Chemistry & Scale-Up: Supports process development and optimization for GMP manufacturing of clinical trial materials.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	(-)-n-[4-[4-[n-Ethyl-n-(6-Fluoro-6-Methylheptyl)Amino]-1(S)-Hydroxybutyl]Phenyl]Methanesulfonamide Fumarate (2:1)
CAS No.	191349-60-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(-)-N-[4-[4-[N-Ethyl-N-(6-fluoro-6-methylheptyl)amino]-1(S)-hydroxybutyl]phenyl]methanesulfonamide fumarate (2:1); (S)-(-)-N-[4-[4-[N-Ethyl-N-(6-fluoro-6-methylheptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide fumarate salt; Fumarate salt of a chiral benzenesulfonamide derivative; 191349-60-7; Chiral sulfonamide intermediate; (S)-enantiomer fumarate salt.
EINECS	Contact for details

Quality Control

Our (-)-n-[4-[4-[n-Ethyl-n-(6-Fluoro-6-Methylheptyl)Amino]-1(S)-Hydroxybutyl]Phenyl]Methanesulfonamide Fumarate (2:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.