Description

2-Chloro-3-Iodopyrazine is a high-purity halogenated pyrazine derivative, a versatile and valuable building block in advanced organic synthesis. Its core value proposition lies in its dual halogen functionality, which enables selective cross-coupling reactions and facilitates the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and Sonogashira couplings to introduce complex substituents.
• Chemical Library Development: Employed in medicinal chemistry for the parallel synthesis and diversification of compound libraries for high-throughput screening.

Basic Information

Item	Detail
Product Name	2-Chloro-3-Iodopyrazine
CAS No.	191340-85-9
Molecular Formula	C4H2ClIN2
Molecular Weight	240.43 g/mol
Synonyms	3-Iodo-2-chloropyrazine; 2-Chloro-3-iodopyrazine; Pyrazine, 2-chloro-3-iodo-; 191340-85-9; 2-Chloro-3-iodo-pyrazine; 3-Iodo-2-chloro-pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Iodopyrazine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.