Description

tert-Butyl 4-(Picolinamido)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core and picolinamide functionality. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is an essential building block for research and production teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Organic Synthesis Reagent: Used in medicinal chemistry research for constructing piperidine-based scaffolds and introducing the picolinamide pharmacophore.
• Biochemical Research: Employed in the development and study of enzyme inhibitors and receptor modulators in academic and industrial R&D settings.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialized, high-value chemicals used in advanced material science and agrochemical research.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(Picolinamido)Piperidine-1-Carboxylate
CAS No.	191087-18-0
Molecular Formula	C16H23N3O3
Molecular Weight	305.37 g/mol
Synonyms	1-Boc-4-(picolinamido)piperidine; 4-(Pyridine-2-carboxamido)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(pyridine-2-carbonyl)amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(picolinamido)piperidine; 4-(Picolinoylamino)-1-piperidinecarboxylic acid tert-butyl ester; N-(1-Boc-4-piperidinyl)picolinamide; BOC-PIPERIDINE-4-PICOLINAMIDE
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Picolinamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.