Description

4 4'-Methylene-13C-Dianiline is a stable isotope-labeled analog of 4,4'-methylenedianiline (MDA), where the central methylene carbon is enriched with carbon-13. This compound is essential for use as an internal standard in quantitative mass spectrometry, enabling precise and accurate analytical measurements. It is primarily required by research laboratories, pharmaceutical developers, and analytical service providers working in areas such as polymer chemistry, environmental monitoring, and metabolomics studies.

Application

• Internal standard for the quantitative LC-MS/MS analysis of 4,4'-methylenedianiline and related aromatic amines.
• Tracer compound in metabolism and pharmacokinetic studies within pharmaceutical R&D.
• Reference material for quality control and method validation in analytical laboratories.
• Use in polymer research to study the degradation and leaching of isocyanate-based materials like polyurethanes.
• Critical component in environmental testing for monitoring occupational exposure and industrial effluent.
• Stable isotope dilution agent in proteomics and metabolomics research for accurate quantification.

Basic Information

Product Name	4 4'-Methylene-13C-Dianiline
CAS No.	190778-00-8
Molecular Formula	C₁₃¹³CH₁₄N₂
Molecular Weight	200.25 g/mol (¹³C labeled)
Synonyms	4,4'-Methylenedianiline-¹³C; MDA-¹³C; Bis(4-aminophenyl)methane-¹³C; 4,4'-Diaminodiphenylmethane-¹³C; 4-(4-Aminobenzyl)aniline-¹³C; DDM-¹³C; Methylenebis(4-aminobenzene)-¹³C; 4,4'-Methylenebis(aniline)-¹³C
EINECS	Contact for details

Quality Control

Our 4 4'-Methylene-13C-Dianiline is manufactured under strict quality systems to ensure high isotopic and chemical purity for demanding analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and impurity profiles. We adhere to relevant standards for high-purity reference materials, and custom purity grades are available to meet specific research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % ¹³C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.