Description

n-(2-Piperazinoethyl)Maleimide is a specialized heterocyclic compound featuring a maleimide group linked to a piperazine moiety via an ethyl spacer. This unique bifunctional structure makes it a valuable intermediate for the synthesis of bioactive molecules and functional polymers. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery and advanced material science. The compound is supplied with a high level of purity to meet the stringent requirements of these applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential therapeutic agents, including kinase inhibitors and other small-molecule drugs.
• Bioconjugation Reagent: Used to modify proteins, peptides, and antibodies via Michael addition to thiol groups, enabling the creation of antibody-drug conjugates (ADCs) and labeled biomolecules.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Employed in the development of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Material Science Research: Utilized in surface modification and the creation of smart materials and hydrogels for biomedical applications.
• Agrochemical Research: Intermediate in the development of novel crop protection agents and pesticides.

Basic Information

Product Name	n-(2-Piperazinoethyl)Maleimide
CAS No.	190714-38-6
Molecular Formula	C10H15N3O2
Molecular Weight	209.25 g/mol
Synonyms	1-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)piperazine; N-(2-(Piperazin-1-yl)ethyl)maleimide; 1-(2-(Piperazin-1-yl)ethyl)-1H-pyrrole-2,5-dione; Maleimide-PEG1-Piperazine; Piperazineethyl Maleimide; 190714-38-6; N-(2-Piperazin-1-ylethyl)maleimide
EINECS	Contact for details

Quality Control

Our n-(2-Piperazinoethyl)Maleimide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.