Description

C16((-2'-Hydroxy) Dihydro Ceramide (D18:0/16:0) is a high-purity, synthetic sphingolipid derivative, a key structural component of the skin's lipid barrier. This compound matters for its role in advanced cosmetic and pharmaceutical research, where it is used to study lipid metabolism, enhance skin barrier repair, and develop next-generation skincare formulations. It is primarily needed by R&D scientists and formulators in the cosmetic, dermatological, and life science industries seeking to innovate in areas of moisturization, anti-aging, and cellular signaling.

Application

• High-Performance Skincare Formulations: As a key active ingredient in moisturizers, anti-aging serums, and barrier repair creams to improve skin hydration and elasticity.
• Dermatological Research: Used as a reference standard or experimental compound in studies of skin barrier function, lipidomics, and ceramide-related disorders.
• Cosmetic Science & Product Development: Incorporated into model systems to test the efficacy and stability of new delivery systems for lipid-based actives.
• Biochemical & Cell Biology Studies: Employed in research on sphingolipid metabolism, cell membrane structure, and apoptosis signaling pathways.
• Pharmaceutical Excipient Development: Investigated for use in topical drug delivery systems to enhance skin penetration and therapeutic outcomes.

Basic Information

Product Name	C16((-2'-Hydroxy) Dihydro Ceramide (D18:0/16:0)
CAS No.	190249-36-6
Molecular Formula	C34H69NO4
Molecular Weight	555.93 g/mol
Synonyms	N-[(2S,3R,4E)-2-Hydroxy-1,3-dihydroxyoctadec-4-en-1-yl]hexadecanamide; Dihydroceramide (d18:0/16:0); (2S,3R,4E)-2-Hydroxy-N-(1-hydroxy-3-hydroxyoctadec-4-en-2-yl)hexadecanamide; Phytosphingosine Ceramide (d18:0/16:0); C16 Dihydroceramide; Synthetic Ceramide AP; Ceramide 2 Analog; Skin-Identical Ceramide
EINECS	Contact for details

Quality Control

Our C16((-2'-Hydroxy) Dihydro Ceramide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress. This material is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.