Description

1-Boc-4-Ethoxycarbonylmethoxypiperidine is a versatile and high-purity piperidine derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a reactive handle for further functionalization while protecting the amine group, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing piperidine or piperazine scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring specific amine functionalities.
• Chemical Research & Development: Serves as a protected synthon in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetics: Employed in the construction of peptide analogs and mimetics where the piperidine moiety is integral to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals for client projects.

Basic Information

Product Name	1-Boc-4-Ethoxycarbonylmethoxypiperidine
CAS No.	189889-45-0
Molecular Formula	C14H25NO5
Molecular Weight	287.35 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-(ethoxycarbonylmethoxy)piperidine; 4-(Carbethoxymethoxy)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-Boc-4-(ethoxycarbonylmethoxy)piperidine; tert-Butyl 4-(ethoxycarbonylmethoxy)piperidine-1-carboxylate; Piperidine, 1-[(1,1-dimethylethoxy)carbonyl]-4-[(ethoxycarbonyl)methoxy]-; 1-Boc-4-(2-ethoxy-2-oxoethoxy)piperidine; Boc-4-(ethoxycarbonylmethoxy)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Ethoxycarbonylmethoxypiperidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.