Description

tert-Butyl 4-(4-Acetylphenyl)-Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research and development chemists, process scale-up engineers, and manufacturers in the global pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for innovative drug discovery and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in the development of antipsychotic and neuroleptic agents.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) for central nervous system (CNS) therapeutics.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-up: Employed in the development and optimization of robust, scalable synthetic routes for commercial pharmaceutical manufacturing.
• Custom Synthesis: Serves as a starting material for the custom synthesis of specialized derivatives and analogs for proprietary research.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	tert-Butyl 4-(4-Acetylphenyl)-Piperazine-1-Carboxylate
CAS No.	189763-86-8
Molecular Formula	C17H24N2O3
Molecular Weight	304.39 g/mol
Synonyms	1-Boc-4-(4-acetylphenyl)piperazine; 4-(4-Acetylphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(4-acetylphenyl)piperazine-1-carboxylate; 1-(4-(1-Boc-piperazin-4-yl)phenyl)ethan-1-one; 4-(4-Acetylphenyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-acetylphenyl)piperazine; BOC-4-(4-Acetylphenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Acetylphenyl)-Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.