Description

5,6-Bis(Bromomethyl)Pyrazine-2,3-Dicarbonitrile is a versatile and highly functionalized heterocyclic building block, primarily valued for its dual reactive bromomethyl groups and electron-withdrawing nitrile substituents. This unique structure makes it a critical intermediate for constructing complex molecular architectures in advanced organic synthesis. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require a reliable, high-purity precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other biologically active heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazine core contributes to specific biological activity.
• Ligand and Chelator Precursor: Serves as a starting material for the synthesis of complex polydentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer and Materials Science: Employed as a cross-linking agent or monomer for creating specialty polymers, conductive materials, or polymers with specific thermal or electronic properties.
• Chemical Linker: The reactive bromomethyl groups allow for facile conjugation to other molecules, making it useful in bioconjugation and the synthesis of molecular probes.
• Research and Development: A valuable tool for academic and industrial R&D chemists exploring new reactions and constructing complex heterocyclic libraries for screening.

Basic Information

Product Name	5,6-Bis(Bromomethyl)Pyrazine-2,3-Dicarbonitrile
CAS No.	189701-21-1
Molecular Formula	C8H4Br2N4
Molecular Weight	315.95 g/mol
Synonyms	2,3-Dicyano-5,6-bis(bromomethyl)pyrazine; 5,6-Bis(bromomethyl)-2,3-pyrazinedicarbonitrile; 2,3-Pyrazinedicarbonitrile, 5,6-bis(bromomethyl)-; Pyrazine-2,3-dicarbonitrile, 5,6-bis(bromomethyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent industry standards. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is available for every batch upon request, detailing all relevant specifications to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.