Description

4,5-Di-o-Caffeoylquinic Acid Methyl Ester is a specialized polyphenolic compound derived from chlorogenic acid. This high-purity reference standard is critical for analytical research, quality control, and the development of nutraceutical and pharmaceutical products. It serves as a key biomarker and active ingredient for researchers and manufacturers in the phytochemical, dietary supplement, and life science industries seeking to standardize and validate their analytical methods.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of herbal extracts and complex botanical matrices in QC/QA laboratories.
• Nutraceutical & Dietary Supplement Research: Acts as a bioactive marker compound for standardizing extracts from plants like Erigeron breviscapus, supporting claims of antioxidant and neuroprotective activity.
• Academic & Bioactivity Studies: Employed in in vitro and in vivo research to investigate potential anti-inflammatory, antioxidant, and metabolic regulatory properties.
• Cosmeceutical Formulation: Incorporated into advanced skincare products for its potential antioxidant benefits, helping to protect skin from environmental stressors.
• Food & Beverage Analysis: Serves as an analytical standard for quantifying chlorogenic acid derivatives in functional foods, coffees, and plant-based beverages.

Basic Information

Product Name	4,5-Di-o-Caffeoylquinic Acid Methyl Ester
CAS No.	188742-80-5
Molecular Formula	C26H24O12
Molecular Weight	528.46 g/mol
Synonyms	4,5-Di-O-caffeoylquinic acid methyl ester; Methyl 4,5-di-O-caffeoylquinate; 4,5-Dicaffeoylquinic acid methyl ester; Breviscapine related compound; Scutellarin intermediate; Dengzhanxixin derivative; Erigeron breviscapus constituent
EINECS	Contact for details

Quality Control

Every batch of 4,5-Di-o-Caffeoylquinic Acid Methyl Ester is produced and tested under strict quality management systems. We provide comprehensive analytical documentation, including HPLC chromatograms and full spectral data (UV, MS, NMR), to ensure identity, purity, and traceability. A Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is supplied with each shipment, supporting compliance with cGMP and ISO 9001 standards for research and manufacturing use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	<10 ppm
Water Content (KF)	<2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.