Description

1-[2-(3-Fluorophenyl)Ethyl]Piperazine 2Hcl is a high-purity, fluorinated piperazine derivative supplied as a dihydrochloride salt, offering enhanced stability and solubility for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and research chemical in the development of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science industries seeking to incorporate a fluorinated phenethylpiperazine moiety into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential central nervous system (CNS) active compounds, including antidepressants, antipsychotics, and cognitive enhancers.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the fluorine atom for improved metabolic stability and bioavailability.
• Chemical Biology Probe: Serves as a precursor for creating tool compounds to study biological pathways and receptor interactions in academic and industrial research settings.
• Ligand Synthesis: Employed in medicinal chemistry programs for constructing complex molecules targeting G-protein-coupled receptors (GPCRs) and other protein families.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring a specific fluorinated aromatic piperazine scaffold.

Basic Information

Item	Details
Product Name	1-[2-(3-Fluorophenyl)Ethyl]Piperazine 2Hcl
CAS No.	188400-93-3
Molecular Formula	C12H17F N2 • 2HCl
Molecular Weight	289.20 g/mol
Synonyms	1-[2-(3-Fluorophenyl)ethyl]piperazine dihydrochloride; 3-Fluorophenethylpiperazine dihydrochloride; 1-(3-Fluorophenethyl)piperazine dihydrochloride; N-(3-Fluorophenethyl)piperazine dihydrochloride; 3-F-PEP dihydrochloride; 1-(2-(3-Fluorophenyl)ethyl)piperazine hydrochloride (1:2); 188400-93-3 (CAS)
EINECS	Contact for details

Quality Control

Our 1-[2-(3-Fluorophenyl)Ethyl]Piperazine 2Hcl is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.