Description

4-Piperazin-1-Yl-Benzoic Acid tert-Butyl Ester is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its core value lies in its piperazine-substituted benzoate structure, which serves as a versatile scaffold for constructing more complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes and enzyme inhibitors for biological pathway studies.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with specific functional properties.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel synthetic route exploration.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-value fine chemicals for client-specific projects.

Basic Information

Product Name	4-Piperazin-1-Yl-Benzoic Acid tert-Butyl Ester
CAS No.	187669-28-9
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	tert-Butyl 4-(piperazin-1-yl)benzoate; 4-(1-Piperazinyl)-Benzoic Acid 1,1-Dimethylethyl Ester; 4-Piperazin-1-yl-benzoic acid tert-butyl ester; Benzoic acid, 4-(1-piperazinyl)-, 1,1-dimethylethyl ester; 1-Boc-4-(4-carboxyphenyl)piperazine (common misnomer); 4-(Piperazin-1-yl)benzoic acid tert-butyl ester; 187669-28-9; tert-Butyl 4-(piperazin-1-yl)benzoate
EINECS	Contact for details

Quality Control

Our 4-Piperazin-1-Yl-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.