Description

2-Cyanopiperazine is a versatile and high-value heterocyclic building block, specifically a piperazine derivative functionalized with a nitrile group. This unique structure makes it a critical intermediate in the synthesis of complex pharmaceutical compounds and advanced materials. It is particularly valuable for medicinal chemistry research and the development of active pharmaceutical ingredients (APIs). Industries including pharmaceuticals, agrochemicals, and specialty chemical manufacturing rely on this compound for its role in constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	2-Cyanopiperazine
CAS No.	187589-36-2
Molecular Formula	C5H9N3
Molecular Weight	111.15 g/mol
Synonyms	2-Cyano-piperazine; Piperazine-2-carbonitrile; 2-Piperazinecarbonitrile; 1,4-Diazacyclohexane-2-carbonitrile; 2-Cyano-1,4-diazacyclohexane; 2-CNPZ; 2-Cyanopiperazine, 98+%
EINECS	Contact for details

Quality Control

Our 2-Cyanopiperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.