Description

tert-Butyl 4-(3-Chlorophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive molecules and active pharmaceutical ingredients (APIs).
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex piperazine-containing molecular frameworks.
• Research & Development: Essential for medicinal chemistry research, lead optimization, and process development in drug discovery programs.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection agents and pesticides.
• Material Science Research: Investigated for the development of specialty polymers and functional materials.

Basic Information

Product Name	tert-Butyl 4-(3-Chlorophenyl)Piperazine-1-Carboxylate
CAS No.	186790-11-4
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	1-Boc-4-(3-Chlorophenyl)piperazine; 4-(3-Chlorophenyl)-1-piperazinecarboxylic acid tert-butyl ester; tert-Butyl 4-(3-chlorophenyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(3-chlorophenyl)piperazine; 3-Chlorophenylpiperazine-1-carboxylic acid tert-butyl ester; 1-Boc-3-chlorophenylpiperazine; 186790-11-4; BOC-3-Cl-Ph-Piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Chlorophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.