Description

tert-Butyl 4-(4-Cyanophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-value, protected piperazine derivative featuring a cyano-substituted aromatic ring. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in modern organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules. The tert-butyloxycarbonyl (Boc) protecting group offers excellent stability under a wide range of reaction conditions, making it indispensable for multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction methodologies.
• Peptidomimetics & Bioactive Molecules: The piperazine core is integral to creating peptidomimetics and other bioactive compounds for drug discovery programs.
• Material Science: Potential monomer or precursor for specialty polymers and advanced functional materials.

Basic Information

Product Name	tert-Butyl 4-(4-Cyanophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	186650-98-6
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	1-Boc-4-(4-cyanophenyl)piperazine; tert-Butyl 4-(4-cyanophenyl)piperazine-1-carboxylate; 4-(4-Cyanophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(4-cyanophenyl)piperazine; Boc-4-(4-Cyanophenyl)piperazine; 186650-98-6; 4-(4-Cyanophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Cyanophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.