Description

tert-Butyl 4-[4-[Amino(Hydroxyimino)Methyl]Phenyl]Tetrahydro-1(2H)-Pyrazinecarboxylate CAS NO 186650-24-8 is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: Used in the construction of complex molecules targeting specific protease enzymes, relevant for antiviral and anticancer therapies.
• Peptidomimetic Development: Integral for creating stable, bioavailable peptidomimetics that mimic natural peptides.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring high-fidelity intermediates.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 4-[4-[Amino(Hydroxyimino)Methyl]Phenyl]Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	186650-24-8
Molecular Formula	C16H24N4O3
Molecular Weight	320.39 g/mol
Synonyms	1(2H)-Pyrazinecarboxylic acid, 4-[4-[(aminoiminomethyl)amino]phenyl]tetrahydro-, 1,1-dimethylethyl ester; 4-[4-(Aminoiminomethylamino)phenyl]tetrahydro-2H-pyrazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4-(amino(imino)methyl)phenyl)piperazine-1-carboxylate oxime; BOC-Piperazine-PBA oxime; (tert-Butoxycarbonyl)-4-(4-(amino(hydroxyimino)methyl)phenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[4-[Amino(Hydroxyimino)Methyl]Phenyl]Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.