Description

Methyl 4-(3-{[(3-Methoxy-5-Methylpyrazin-2-Yl)[(2-Methylpropoxy)Carbonyl]Amino]Sulfonyl}Pyridin-2-Yl)Benzoate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular action. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates, especially in oncology and metabolic disease research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for novel APIs under preclinical and clinical investigation.
• Chemical Biology Research: Used as a probe or precursor in studying enzyme inhibition and receptor-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for new drug molecules.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and synthetic methodology projects.

Basic Information

Product Name	Methyl 4-(3-{[(3-Methoxy-5-Methylpyrazin-2-Yl)[(2-Methylpropoxy)Carbonyl]Amino]Sulfonyl}Pyridin-2-Yl)Benzoate
CAS No.	186497-89-2
Molecular Formula	C24H26N4O6S
Molecular Weight	498.55 g/mol
Synonyms	Methyl 4-[3-[[(3-Methoxy-5-methylpyrazin-2-yl)carbamoyl]sulfamoyl]pyridin-2-yl]benzoate; 186497-89-2; Benzoic acid, 4-[3-[[[[(3-methoxy-5-methyl-2-pyrazinyl)amino]carbonyl]amino]sulfonyl]-2-pyridinyl]-, methyl ester; Methyl 4-(3-((((3-methoxy-5-methylpyrazin-2-yl)carbamoyl)amino)sulfonyl)pyridin-2-yl)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(3-{[(3-Methoxy-5-Methylpyrazin-2-Yl)[(2-Methylpropoxy)Carbonyl]Amino]Sulfonyl}Pyridin-2-Yl)Benzoate adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting customer and research standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.