Description

1-Piperazineethanol, α-(Aminomethyl)- is a versatile bifunctional organic compound featuring both a piperazine ring and an ethanolamine side chain with an additional aminomethyl group. This unique structure makes it a valuable high-purity building block for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries who require reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular diseases.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Agrochemical Research: Employed as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Bioconjugation: Useful in the development of linkers for antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes and tools used in biochemical and cellular studies.

Basic Information

Product Name	1-Piperazineethanol, α-(Aminomethyl)-
CAS No.	186343-40-8
Molecular Formula	C7H17N3O
Molecular Weight	159.23 g/mol
Synonyms	2-[(Aminomethyl)(piperazin-1-yl)methyl]ethanol; 1-Piperazineethanol, 4-(aminomethyl)-; α-(Aminomethyl)-1-piperazineethanol; 4-(Aminomethyl)-1-piperazineethanol; (Piperazin-1-yl)(2-hydroxyethyl)methyl]methanamine; 1-(2-Hydroxyethyl)piperazine-4-methanamine; 4-(2-Hydroxyethyl)piperazine-1-methanamine
EINECS	Contact for details

Quality Control

Our 1-Piperazineethanol, α-(Aminomethyl)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.