Description

(E)-3-Methoxy-4-((2-(Pyridin-3-Yl)-5,6-Dihydropyridin-3(4H)-Ylidene)Methyl)Phenol Dihydrochloride is a high-purity, non-racemic chiral compound of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring a dihydropyridine core linked to phenol and pyridine moieties, makes it a valuable synthetic intermediate and a potential pharmacophore. This compound is primarily utilized by medicinal chemists and process development scientists working on novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Probe Development: Employed in the design and synthesis of probes for studying enzyme mechanisms or biological pathways.
• Process Chemistry: Used in route scouting and scale-up studies for the production of complex active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for cutting-edge organic synthesis and pharmacology projects.

Basic Information

Product Name	(E)-3-Methoxy-4-((2-(Pyridin-3-Yl)-5,6-Dihydropyridin-3(4H)-Ylidene)Methyl)Phenol Dihydrochloride
CAS No.	185247-71-6
Molecular Formula	C19H21Cl2N2O2
Molecular Weight	380.29 g/mol
Synonyms	3-Methoxy-4-[(E)-[2-(3-pyridinyl)-3,4-dihydro-2H-pyridin-5-ylidene]methyl]phenol dihydrochloride; Phenol, 3-methoxy-4-[(E)-[2-(3-pyridinyl)-3,4-dihydro-2H-pyridin-5-ylidene]methyl]-, dihydrochloride; (E)-3-Methoxy-4-((2-(pyridin-3-yl)-1,4,5,6-tetrahydropyridin-3-yl)methylene)cyclohexa-2,5-dienone dihydrochloride; 185247-71-6; 3-Methoxy-4-((E)-((2-(pyridin-3-yl)-1,2,3,4-tetrahydropyridin-5-yl)methylene)cyclohexa-2,5-dienone dihydrochloride
EINECS	Contact for details

Quality Control

Our (E)-3-Methoxy-4-((2-(Pyridin-3-Yl)-5,6-Dihydropyridin-3(4H)-Ylidene)Methyl)Phenol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC purity assay, chiral purity determination, and structural confirmation to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing all test results are provided and traceable to primary reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.