Description

3-(4-Trifluoromethyl-Phenyl)-Piperazin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazinone core and trifluoromethylphenyl substituent. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged scaffold.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of assays for receptor binding studies.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the 3-(4-trifluoromethylphenyl)piperazin-2-one moiety into more complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	3-(4-Trifluoromethyl-Phenyl)-Piperazin-2-One
CAS No.	185110-29-6
Molecular Formula	C11H11F3N2O
Molecular Weight	244.21 g/mol
Synonyms	3-[4-(Trifluoromethyl)phenyl]-2-piperazinone; 1-(4-Trifluoromethylphenyl)piperazin-2-one; 3-(4-Trifluoromethylphenyl)piperazin-2-one; 2-Piperazinone, 3-[4-(trifluoromethyl)phenyl]-; 185110-29-6; 3-(4-Trifluoromethylphenyl)-2-piperazinone
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethyl-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.